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  Phases |Inertsil CN-3

     Key Benefits and Features of Inertsil CN-3 (aka Cyano, or Nitrile) - Part of the Advanced Inertsil 3-Series of Phases
   Virtually perfect peak shape for most bases and acids
   Unique selectivity in both reverse phase and normal phase modes.
   Exceptional physical and chemical durability provides long column life
   Vast database of chromatographic applications available to assist in method development
   Very low operating back pressure

Figure 1 - Separation of Estrogens using Inertsil CN-3 column in both normal and reverse-phase modes
Column: CN-3 250 x 4.6mm ; Normal Phase Eluent: Hexane/EtOH 90/10 Flow:1.0 ml/min Temp: 40°C Detection: UV at 220nm  Sample: As indicated Reverse Phase Eluent: MeCN/Water 35:65 Flow: 1.0 ml/min Temp: 25°C Detection: UV at 220nm  Sample:As indicated

Notes: 
The versatility of Inertsil CN-3 makes is a useful alternative when ODS or C8 phases don't work. 

GL Sciences' unique, super high density bonding procedure has produced a CN phase that eliminates the instability and irreproducibility that plagued standard CN phases.  CN-3 offers unique selectivity, long column operating life, and excellent peak shapes in both reverse phase and normal phase modes.

GL Sciences has compiled a vast collection of chromatographic applications data on CN-3 and their other phases which can assist you in method development.  These can be accessed in the InertSearch program.
 
Inertsil CN-3 is available in 3, 5 micron particle sizes in column configurations ranging from capillary to 50mm ID preparative sizes.

The Inertsil 3-series represents a major advance in performance over the original Inertsil 2-Series. Inertsil 3-Series phases, including ODS-3, ODS-SPRINT, ODS-3V, ODS-P, ODS-EP, C8-3, Ph-3, NH2, Diol, SIL-100Å, are based on a purer, higher surface area silica which is specially manufactured to provide maximum bonded phase coverage.  The result is a series of columns which provide excellent peak shapes using simple eluents while operating at low pressure.
        Click here for a detailed PDF on Inertsil CN-3

Particle
Size
Particle
Shape
Surface
Area
Pore
Size
Pore
Volume
Silica
Purity
Bonded
Phase
End-
Capping
Carbon
Load
pH
Range
USP
Code
3, 5, 8 µm Spherical 450 m2/g 100Å 1.05 mL/g 99.999% Cyanopropyl
Groups
No 14% 2 - 7.5 L10