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Phases | Titanshere

Titansphere (TiO2) Titanium Dioxide HPLC Cartridges, Columns, Capillaries, and Pipette Tips Highly Selective Enrichment of phosphorylated peptides from complex peptide mixtures      Extremely selective for phosphorylated peptide extraction and/or enrichment from proteolytic digests    More selective than IMAC for most applications    Available in HPLC cartridge, column, capillary, as well as low-pressure Pipette-Tip formats   Titansphere has been found to be particularly effective in the selective enrichment of phosphorylated peptides from proteolytic digests. Titansphere offers greater selectivity for phosphopeptides than alternative methods, such as IMAC (immobilized metal affinity chromatography). Typically, IMAC shows significant binding of non-phosphorylated peptides which have multiple acidic residues. This problem is easily eliminated by using Titansphere. Typically, PEEK cartridges or non-metal capillaries containing Titansphere are used to selectively bind phosphorylated peptides from a peptide mixture. The phosphorylated peptides are then eluted from the column onto a reverse-phase HPLC column for further characterization or analyzed directly by MS. More information...   Please check the InertSearch database for more information.